This thesis describes the findings of species of the order Octopoda in the Northern and Central Adriatic Sea collected during the MEDITS expeditions in the period from 1996 to 2019. For all found species, depth and spatial distribution, biomass and abundance indices, sex ratios and proportions of gonad maturity stages were presented. During these studies, a total of eight species from this order were found. All species have already been recorded in the Adriatic Sea, and apart from three economically significant species (Octopus vulgaris, Eledone cirrhosa, Eledone moschata), others have rarely been found. For example, species Pteroctopus tetracirrhus and Macrotritopus deffilippii were recorded with only a few specimens throughout the study period. Octopus vulgaris and Eledone moschata species were found only on the continental shelf, while Eledone cirrhosa, Octopus macropus, Pteroctopus tetracirrhus and Scaeurgus unicirrhus were also found at depths greater than 200 m. Of all octopuses only the species Octopus salutii was recorded at depths greater than 400 m.